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Sinequan Medication - Uses & Side Effects

Generic Name: Doxepin hydrochloride

DOXEPIN (Sinequan®) belongs to a group of medicines known as tricyclic antidepressants. Doxepin is used to affects the chemicals in the brain that may cause depression. Sinequan is used to treat depression, panic disorders, depression related to alcoholism or major illness, psychotic depression, chronic pain from a variety of conditions, fibromyalgia and also decrease the incidence of chronic headache or migraine, ulcers, itching, and insomnia. Sinequan generally used to treat tension, fear, guilt, and worry, and also improving mood, energy, and sleep.

Sinequan Dosage

  • The starting dose should be usually 75 milligrams per day. your doctor may increase or decrease the dosage as you needed.
  • Mostly the ideal dose ranges should be 75 milligrams per day to 150 milligrams per day or it can be low as 25 to 50 milligrams per day.
  • You can take single dose once a day or you can divide single dose into smaller doses. If you are taking Sinequan medicine once a day, then you should take dose 150 milligrams at bedtime.
  • If you are older people, then you should started on a low dose.

Uses of Sinequan

  • Sinequan medicine is a tricyclic antidepressant used to treat depression.
  • Doxepin is used to improve the symptoms of anxiety such as include feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia, and thoughts of death or suicide.

Side Effects of Sinequan

Before taking Sinequan medicine, first discuss about the possible side effects of this medicine with your doctor. If you feel any change in intensity, inform your doctor immediately. Because your doctor can determine if it is safe for you to continue taking Sinequan or you should not used further. Side effects may include:

  • Blurred vision
  • trouble urinating
  • rash
  • water retention
  • drowsiness
  • dry mouth
  • itchy or scaly skin (pruritus)
  • light sensitivity
  • constipation
  • nausea
  • rapid or irregular heartbeat
  • dizziness
  • low blood pressure

Warnings and precautions before taking Sinequan:

  • You should not stop Sinequan medicine without taliking with your doctor. Because if you will stop the medicine suddenly, Abrupt withdrawal may cause symptoms such as nausea, vomiting, loss of appetite, headache, giddiness, chills, insomnia or anxiety.
  • When you are taking Sinequan medicine, then you should not drink alcohol. Because it may cause to another serious effects, So use medicine with caution.
  • After taking Sinequan medicine, you will be feel some sleepy and this medicine may reduce your ability to drive or operate machinery safely. So do not drive or operate machinery and do not perform any daily activities where you requiring alertness.

Drug Interaction :-

Before taking any other drugs with Sinequan medicine, Consultis with your doctor. Because it may be increased, decreased, or altered the effect of Sinequan medicine or it may cause to the other serious effect. So it is especially important to check with your doctor before combining Sinequan with the following:

  • Propafenone (Rythmol)
  • Other antidepressants such as Elavil and Serzone
  • Quinidine (Quinidex)
  • Cimetidine (Tagamet)
  • Clonidine (Catapres)
  • Flecainide (Tambocor)
  • Guanethidine (Ismelin)
  • Major tranquilizers such as Compazine, Mellaril, and Thorazine
  • Carbamazepine (Tegretol)
  • Tolazamide (Tolinase)
  • Antidepressants that act on serotonin, such as Celexa, Lexapro, Prozac, Zoloft, and Paxil

After taking Sinequan medicine, If you feel that overdose is suspected. Contact your doctor immediately. Symptoms of Sinequan overdose may include:

  • Agitation
  • vomiting
  • coma
  • stupor
  • confusion
  • convulsions
  • severely low blood pressure
  • dilated pupils
  • rigid muscles
  • disturbed concentration
  • overactive reflexes
  • drowsiness
  • irregular heartbeat
  • hallucinations
  • high or low body temperature

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