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Depakene Medication - Uses & Side Effects

Generic Name: Valproic acid

VALPROIC ACID capsules (Depakene®) affects chemical in the body that may cause to occur seizures. This drug also used to treat bipolar disorder, mania, migraines, and behavioral problems. Depakene, an epilepsy medicine, is used to treat certain types of seizures and convulsions. Valproic acid, valproate sodium, and divalproex all this medicine belong to the group of medicines is known as anticonvulsants. Depakene control seizures by reducing abnormal electrical discharges and convulsions.

Depakene Dosage

  • Mostly starting dose is 10 to 15 milligrams per 2.2 pounds of body weight per day. Actually the initial dosage depend on your weight so your doctor may increase or decrease dose according to your weight.
  • Your doctor may increase the dose at weekly intervals by 5 to 10 milligrams per 2.2 pounds per day until seizures are controlled or side effects become too severe.
  • If stomach upset develops, the dose may be increased more slowly.
  • The initial or daily dose should not exceed 60 milligrams per 2.2 pounds per day.
  • Dosage continued according to weight, effectiveness, blood levels, and side effects.
  • Depakene should be used with food to reduce digestive problems.

Uses of Depakene

  • Depakene medicine's is used to prevent seizures.
  • Valproic acid is used to treat various types of seizure disorders. Valproic acid is sometimes used together with other seizure medications.
  • Valproic acid may also be used for purposes other than those listed in this medication guide.
  • It is also approved to treat bipolar disorder and also use to treat migraine headaches.
  • It is also helpful as an add-on therapy in patients with multiple seizure types that include absence seizures.

Side Effects of Depakene

The possible side effects may occur due to depakene and unlikely listed effects given below:

  • Abdominal cramps
  • amnesia
  • breathing difficulty
  • depression
  • diarrhea
  • dimmed or blurred vision
  • drowsiness
  • hair loss
  • indigestion
  • infection
  • involuntary eye movements
  • loss or increase in appetite
  • nausea
  • nervousness
  • ringing in the ears
  • sleeplessness
  • swelling of the arms and legs due to fluid retention
  • throat inflammation
  • tremors
  • vomiting

Warnings and precautions before taking Depakene:

  • Depakene should be taken cautiously by those patients that have liver disease and by the elder patients.
  • Depakene medication should not be discontinued immediately, due to the possibility of life-threatening seizure activity.
  • This medicine may cause dizziness or drowsiness.
  • This medication has rarely caused serious (sometimes fatal) liver problems. Children less than 2 years may be severe liver problems, especially if they have metabolic problems, severe seizures with mental retardation, brain disease (organic) or if they take more than one drug for seizures.
  • This medication has rarely caused severe (sometimes fatal) disease of the pancreas (pancreatitis). This problem may occur at any time during therapy.
  • Becareful when you will take valproic acid, valproate sodium, and divalproex , if the acid pass into the breast milk it may effect the nursing baby, but their effect on the nursing baby is not known. So It may be necessary for you to take another medicine or to stop breast-feeding during treatment with valproic acid, valproate sodium, or divalproex. So consult your doctor or first known about the effects may occur when you will start valproic acid.
  • Do not stop taking the depakene medication even if you feel better. It is important to take valproic acid continue to prevent seizures from recurring.

Drug Interaction :-

If you taken depakene with other drugs so the effect of depakene may be increased or decreased or it may be altered. So consult your doctor before combining depakene with the following drugs that given below and the drug interaction depakene with other drugs, then it may cause to produced new effects.

  • Amitriptyline (Elavil)
  • Aspirin
  • Barbiturates such as phenobarbital and Seconal
  • Blood-thinning drugs such as Coumadin and Dicumarol
  • Carbamazepine (Tegretol)
  • Clonazepam (Klonopin)
  • Diazepam (Valium)
  • Ethosuximide
  • Felbamate (Felbatol)
  • Lamotrigine (Lamictal)
  • Merrem IV (meropenem for injection)
  • Nortriptyline (Pamelor)
  • Phenytoin (Dilantin)
  • Primidone (Mysoline)
  • Rifampin (Rifater)
  • Tolbutamide (Orinase)
  • Zidovudine (Retrovir)

If you feel the overdose is suspected then consult your doctor immediately. Symptoms of a valproic acid overdose may include:

  • sleepiness or drowsiness
  • shallow breathing
  • weak pulse
  • loss of consciousness.

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