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Chlamydial InfectionsUrethritis in men, cervicitis in women, and - much less commonly in the United States - lymphogranuloma venereum in both sexes all result from chlamydial infections. And all are linked to one organism: Chlamydia trachomatis. These infections are the most common sexually transmitted diseases in the United States. Children born of infected mothers may contract associated otitis media, pneumonia, and trachoma inclusion conjunctivitis during passage through the birth canal. Although trachoma inclusion conjunctivitis seldom occurs in the United States, it's a leading cause of blindness in Third World countries. CausesChlamydial infection may be caused proctitis and conjunctivitis. Chlamydia infection is caused by the organism Chlamydia trachomatis. Chlamydia is transmitted through unprotected sex. Chlamydia may also cause Reiter's Syndrome. Barrier methods of contraception, especially condoms, thwart the transmission of chlamydia. Chlamydia trachomatis may be caused the following conditions:
Symptoms and Signssymptoms do occur, they can include:
Diagnostic testsLaboratory tests provide definitive diagnosis of chlamydial infection. A swab culture from the infection site (urethra, cervix, or rectum) usually establishes urethritis, cervicitis, salpingitis, endometritis, and proctitis. Culture of aspirated blood, pus, or cerebrospinal fluid establishes epididymitis, prostatitis, and lymphogranuloma venereum. If the infection site is accessible, the doctor may first attempt direct visualization of cell scrapings or exudate with Giemsa stain or fluorescein-conjugated monoclonal antibodies. However, tissue cell cultures are more sensitive and specific. Serologic studies to determine previous exposure to C. trachomatis include complement fixation tests and immunofluorescence microscopy. The enzymelinked immunosorbent assay detects the C. trachomatis antibody as effectively as the immunofluorescence microscopy test and is useful as a screening test. TreatmentThe recommended treatment for chlamydial infection consists of doxycycline or tetracycline. The patient can receive ofloxacin or azithromycin. A patient with lymphogranuloma venereum needs extended treatment. Prevention
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